The match was Wickham's first first-team start in over two years and to score such a crucial goal was an ideal way to mark the moment in his continued return in red and blue.
Looking back on the goal, he said, "It was a massive relief, we got ourselves in the lead which was good and we were saying at half time that it could have been 4-0 if we took our chances and were clinical in the end, but I think the performance was as professional as it could have been from start to finish."
Wickham has tasted Cup success before in red and blue, as he helped the Eagles reach the 2016 FA Cup Final. Palace beat Spurs that year, too, and the 25-year-old forward expressed his confidence that the south Londoners can enjoy a similar campaign this year.
He said, "I think we've definitely got the squad to do it [go on a Cup run], we showed that today, we made a few changes but whoever the gaffer decides to put on the field can definitely put in a performance."
And squad depth in particular has been increased in Wickham's area of the field, with both he and fellow front-man Christian Benteke returning from injury over recent weeks.
"It's good," Wickham said, "it's not just Wilf and Andros, we can all share the load. We've got Jordan, Christian's just come back and myself, we look strong all the way from the back to the front."
But it was at the back where headlines were stolen most emphatically, as club legend Julian Speroni kept the all-time highest number of clean sheets guarding his goal today.
Praising the shot-stopper, Wickham mused, "He's been a very, very good servant and a top guy. It's well deserved and you can see why he's such a legend here; the fans love him and the performance he put in today, he showed what a professional he is and he's still got the attributes of a top goalkeeper."
To watch Wickham's full interview, see what Speroni had to say in return to him and Roy Hodgson's post-match press conference, head over to Palace TV now. If you're reading in the app, just click 'Palace TV'.