Whereas Palace appeared to tire in the early stages of extra-time, PSV seemed rejuvenated, more dominant in the immediacy of the restart than at any other point in the game.
Their goalscoring opportunities came thick and fast.
Captain Mathijs Tielemans hit the bar with a looping volley from a half-cleared corner; a double deflection forced Owen Goodman into an athletic save; and numerous pull-backs kept Palace centre-backs Balmer and Sean Grehan on their toes.
When the goal almost inevitably arrived, it was desperately unlucky from a Palace perspective, another low ball towards the penalty spot met by Jason Van Duiven, whose resulting strike deflected up and over Goodman’s reach.
The Eagles were struggling to build attacks as PSV kept the ball for long stretches, but they did come close to finding an equaliser with the last kick of the half: Banks, from almost an identical position, this time bending narrowly wide.
Into the second-half of extra-time and, while Palace – re-energised with the introduction of a number of substitutes – did begin to threaten once more, the visitors’ greater experience of senior football started to tell.
The closest Palace came was with a looping effort from Phillips shortly after the restart but Schiks, to his credit, produced a save at full-stretch to deny the midfielder.
Long throws, free-kicks, balls forward – Palace threw everything at it, but on this occasion, the Dutch side stood firm.
With both sets of players tiring, the match became scrappy in its closing minutes – but there was still time, with virtually the last action of the match, for Colyn to bend a free-kick over the wall and into the top corner to seal PSV’s victory.
A disappointing end for Palace to a remarkable journey in their first-ever season in the Premier League International Cup.
Yet you sensed, as Palace’s stars of the future stood in front of a still-packed Holmesdale Road end, serenading and applauding them well beyond the full-time whistle, the memories – these experiences – will abide.
Crystal Palace U21s: Goodman (GK), Rodney, Grehan, Balmer, Adaramola (Watson, 105), Ozoh (Omilabu, 105), Wells-Morrison, Phillips, Rak-Sakyi (Mooney, 78), Street (Raymond, 117), Banks (Umeh, 105).
Subs not used: Izquierdo (GK), Imray.
Jong PSV: Schiks (GK), Comenencia, Seelt (Tytens, 45), van de Blaak, Leysen, Tielemans, Sealy (Priske, 65), Colyn, van Duiven (Arts, 115), Nassoh, Babadi (Jiminez, 117).
Subs not used: Peersman (GK), Dams, van den Heuvel.