Following the sale of James Daly to Bristol Rovers, Rob Street comes in to leads the line after being used as a substitute in the recent game against Cardiff City.
Brandon Aveiro was substituted against the Bluebirds after taking a knock, however, the attacking-midfielder is fit enough to start against the Robins.
Malachi Boateng, John-Kymani Gordon and Aidan Steele have all been selected to start by Derry with a total of seven personnel changes made from last Wednesday's starting XI.
Palace: Webber, Trialist, Mitchell, M.Boateng, Hobbs, Rich-Baghuelou, Pierrick, Steele, Gordon, Street, Aveiro.
Subs: Trialist, Russell, Thiselton, Mensah, Addy.