After a goalless first 45 minutes, Palace turned on the style in the second-half, scoring five against Pompey.
Annabel Blanchard got a brace on her return to the club, whilst debutant Lola Brown, who arrived on loan from Chelsea this week, also scored twice.
Molly-Mae Sharpe also got on the scoresheet, as Jo Potter's side ran riot in South London.
Check out the best images from the game in the gallery below.
